SaferWorldbyDesign SOT 2025 Recap
Supporting the EPA’s Important Work in Toxicology
Due to current U.S. government travel restrictions, EPA scientists could not attend SOT 2025 in person this year, but their vital work should still be recognized. We wanted to highlight their contributions by sharing their latest research, which is now available online in lieu of the usual in-person presentations. Explore their SOT 2025 work presentations here: https://www.epa.gov/chemical-research/society-toxicology-sot-2025-conference
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For SaferWorldbyDesign and our partners, it was a productive week in sunny Orlando, where we had the chance to connect, learn, and share updates on tools and integrated solutions that support safer and sustainable product design. Here are a few highlights from across the SaferWorldbyDesign ecosystem:
RISK-HUNT3R & ASPIS
Progress from RISK-HUNT3R was presented at SOT, including participation in the joint ASPIS booth, where the spotlight was on advancing risk assessment through data-driven tools and integrated approaches. The collaborative projects in this cluster are focused on building a knowledge infrastructure for next-generation risk assessment, helping to pave the way for more predictive, transparent, and informed decision-making.
https://aspis-cluster.eu/
▶️ Watch the interview with Barry Hardy [embedded above] to hear more about the goals and outcomes of the RISK-HUNT3R project.
OpenTox at SOT 2025
OpenTox participated with a booth at SOT, focused on its activities advancing global collaboration and open science in predictive toxicology.
What’s Coming in 2025 for OpenTox?
- The OpenTox 2025 Virtual Conference – A global forum for discussion, innovation, and collaboration (13 - 17 October, 2025)
- Hands-on Training and Workshops – Practical sessions on in silico modeling, NAMs, and AI-driven risk assessment.
Next trainings:
- OpenTox 2025 Hackathon - 5/12/2025 - 5/16/2025
- OpenTox 2025 Summer School - 7/21/2025 - 7/25/2025
💡 Join the OpenTox Community! Whether you’re a student, researcher, industry professional, or regulator, you can get involved by attending events, participating in discussions, and becoming a member. Interested? Visit OpenTox.net to learn more!
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- InSphero - InSphero showcased their 3D InSight Liver Microtissues Platform, a cutting-edge in vitro model for hepatotoxicity studies. Download the poster here.
- MultiCase - MultiCase demonstrated how computational toxicology is becoming more accessible. Talk: "Practical In Silico Solutions for Common Toxicological Challenges". Presentations available online here: https://multicase.com/research/
- Biopredic - Biopredic highlighted their work in liver models and in vitro systems, supporting the development of more physiologically relevant NAMs.
- BioDetection Systems - BDS continues to innovate in environmental toxicology and bioassay-based methods. Their poster presentation (J453) focused on applying their technologies in risk screening strategies.
- Biobide - Biobide showcased their work on zebrafish as a New Alternative Method for developmental neurotoxicity testing.
- Istituto Mario Negri - Their team presented exciting work on pharmacological research and advanced modeling with poster sessions: K555, N715
- TissUse - TissUse explained updates on their organ-on-a-chip technology, helping to mimic human biology more closely in safety testing.
- Senzagen - Senzagen led a session focused on advancing skin sensitization testing with NAMs.
- Smart Tox - Presented their poster on neurotoxicity testing and predictive tools.
- TERA - TERA highlighted their signature Dose-Response Assessment Boot Camp, with the next course scheduled for May 5-9, 2025.
- Vrije Universiteit Amsterdam - Presented on placental models for micro/nanoplastics toxicity testing—an important step forward in understanding developmental exposure.
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