SSbD Workshop
Workshop Overview - November 6, 2024
13.30 SSbD Overview of Hands-on SSbD Workshop Activities
Barry Hardy (Edelweiss Connect)
We provide an overview of the application of the Safe and Sustainable by Design (SSbD) Framework, methods and tools and the exercises we will pursue in the workshop*. The goal is to (re)design a product to reduce hazards and environmental impacts without compromising functionality. We will include use of the current proposed SSbD framework from the EC JRC, in addition to discussion of criticisms, variations and potential optimisation in practical application.
13.40 Hazard Characterization - Indre Piragyte-Langa Oliva (Edelweiss Connect) and Joanke van Dijk (EMPA)
- Objective: Evaluate hazard assessment using New Approach Methods (NAMs) and data.
- Task: Participants will analyse a set of alternative ingredients for a product using data and models to assess the hazard potential including uncertainty. The group will discuss whether more data needs to be generated to support decision making and select potential in vitro experiments for data gap filling and uncertainty reduction.
- Tools: Utilisation of modelling software and databases such as OECD QSAR Toolbox, VEGA, SaferSkin, SaferWorldByDesign workflow solutions.
14.30 Product Characterization Data Management - Pascal Ankli (Edelweiss Connect)
- Objective: Participants will learn to organise and manage product materials characterization protocols and data efficiently with goals for adhering to quality and FAIR standards.
- Task: Introduction to characterisation data template design based on standardised approaches (e.g., REMBI for images). We will review how templates and workflows can be used to organise protocols and data for characterisation experiments including determination of physical-chemical properties, biological testing and machine learning.
- Tools: ACCORDs Knowledge Infrastructure, tools, and workflow*.
15.15 Coffee Break
15.30 Environmental Scoring of Product Ingredients - Barry Hardy (Edelweiss Connect)
- Objective: Evaluate the environmental impact of product ingredients and explore substitutions.
- Task: Participants will examine the properties of a formulation including selecting alternatives to ingredients for a substitution. Using SmartSafety the group will score each ingredient in a formulation for environmental impact and attempt to narrow down options to best selections.
- Tools: SmartSafety.
16.00 Life Cycle Assessment of Product Materials - Thomas Arblaster (University of Leiden)
- Objective: Understand the application of life cycle analysis to product ingredients and evaluating potential substitutions.
- Task: Using life cycle assessment the group will evaluate data analysis and modelling approaches to inventory and impact analysis.
- Tools: Excel, OpenLCA
16.45 Wrap-up discussion
- Objective: Discuss the challenges and roadblocks to application of SSbD methods.
- Task: Participants will discuss issues and challenges in SSbD methods, identify where critical data gaps could appear and consider methods for modelling or obtaining the necessary data for decision making.
- Tools: Discussion on strategies such as high-throughput screening, data sharing, leveraging public databases or use of modelling approaches (e.g., computational science, machine learning, AI).
17.15 Reception
PREPARATION
No prior SSbD application experience is required. We will work through problems using methods and web-based tools that the group can follow. Participants are encouraged to bring a laptop to fully engage with the interactive components of the workshop.
*This work was conducted with funding support from the EU-funded ACCORDS and SSbD projects
