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SaferSkin™ skin sensitization app

What is SaferSkin™ skin sensitization app?

  • Web application used for predicting ingredient’s potential to cause skin sensitisation, without animal testing.
  • The application applying integrated strategies of safety assessment to skin sensitisation.
  • Combines the top three approaches for accurate predictions of skin sensitisation.
  • Applies state-of-the-art science to workflows over the entire discovery and development funnel, to regulatory acceptance and registration.

The app can be used for:

  • Hazard identification, classification, and labeling under the Globally Harmonised System of Classification and Labelling of Chemicals (GHS) scheme (UN 2013).
  • Quantitative risk assessment (QRA) especially when combined with in vivo evidence on analogs.
  • Development of an efficient testing strategy, as a decision strategy tool.

Saferskin screenshot 4

Main features

  • Comparison of 3 approaches: Bayesian Network, ‘2 out of 3 weight of evidence’, multiple regression
  • Category prediction with confidence levels
  • Simple to use interface
  • Single compound input submission - entered as SMILES or drawn
  • Physical properties calculated
  • LLNA pEC3 & EC3 values from 50-90th percentile confidence

The application

Start using the application.


We offer three different license options.


Tutorials on application use and reports.


SaferWorldbyDesign integrates in silico and in vitro methods to develop standard and premium Integrated Approaches to Testing and Assessment (IATAs), including methods that support ingredient and formulation screening and testing, product design and the preparation of Regulatory Dossiers.


Edelweiss Connect GmbH is registered as a limited company with Handelsregisteramt of Kanton Basel-Stadt

Swiss ID (UID) number: CHE-114.414.615

Copyright | SaferWorldbyDesign 2022