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Vrije Universiteit Amsterdam

Testing of substances in renal epithelial cells (cell line, iPSC or primary) and toxicity assessment


  • Testing of substances in renal epithelial cells (cell line, iPSC or primary) and toxicity assessment
  • Mitochondrial toxicity assessment
  • Phase I and Phase II Metabolism in human liver extracts and/or recombinant preparations
  • Molecular docking, molecular dynamics and site of metabolism prediction
  • Consultation on most appropriate in vitro models and assays

See more on Mechanistic toxicology

SaferWorldbyDesign

SaferWorldbyDesign integrates in silico and in vitro methods to develop standard and premium Integrated Approaches to Testing and Assessment (IATAs), including methods that support ingredient and formulation screening and testing, product design and the preparation of Regulatory Dossiers.

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