SaferNeuron™
Your interactive portal for expert-led neurotoxicity risk assessment, adhering to the 3R principles and sustainability Green Goals
Welcome to
SaferNeuron™
Welcome to SaferNeuron, Your interactive portal for expert-led neurotoxicity risk assessment, adhering to the 3R principles (Replace, Reduce, Refine) [1] and sustainability Green Goals.
Our specialists provide tailored strategies to help you evaluate the neurotoxic potential of your compounds and materials. Using an integrated, tiered approach, we bring together in silico prediction tools, in vitro assays, data management based on the Findable, Accessible, Interoperable and Reusable (FAIR) principles [2] and expert consultancy to deliver comprehensive risk assessments tailored to your needs and regulatory requirements. Thereby, we use New Approach Methodologies (NAMs) [3] in an Integrated Approach to Testing and Assessment (IATA) [4].
Explore more about our business proposition:
Explore SaferNeuron by navigating the content bar, click on any topic to reveal detailed information below. The content updates dynamically with each selection.
SaferNeuron Events
Workshop on SaferNeuron Characterisation
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Webinar on Cosmetic Assessment
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Webinar on
Conciousness
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Webinar on
Conciousness
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References
- [1] Olsson, I. A. S.; Franco, N. H.; Weary, D. M.; Sandøe, P. The 3Rs Principle – Mind the Ethical Gap!
- [2] Wilkinson, M. D.; Dumontier, et al. The FAIR Guiding Principles for Scientific Data Management and Stewardship. Sci Data 2016, 3, 160018.
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[3] Development of a Roadmap for Action on New Approach Methodologies in Risk Assessment | EFSA.
- [4] Integrated Approaches to Testing and Assessment (IATA) - OECD.
- [5] Blum, J.; Masjosthusmann, S.; Bartmann, et al., Establishment of a Human Cell-Based in Vitro Battery to Assess Developmental Neurotoxicity Hazard of Chemicals. Chemosphere 2023, 311, 137035.
- [6] ACCORDs.
- [7] Wilkinson, M. D.; Dumontier, M.; Aalbersberg, et al., The FAIR Guiding Principles for Scientific Data Management and Stewardship. Sci Data 2016, 3, 160018.
- [8] Sarkans, U.; Chiu, W.; et al., REMBI: Recommended Metadata for Biological Images—Enabling Reuse of Microscopy Data in Biology. Nat Methods 2021, 18 (12).
- [9] Leigh, R.; Gault, D.; Linkert, M.; Burel, J.-M.; Moore, J.; Besson, S.; Swedlow, J. R., OME Files - An Open Source Reference Library for the OME-XML Metadata Model and the OME-TIFF File Format. November 19, 2016.
- [10] Allan, C.; Burel, J.-M.; et al., OMERO: Flexible, Model-Driven Data Management for Experimental Biology. Nat Methods 2012, 9 (3), 245–253.
- [11] Digital Product Passport - European Commission.
- [12] Jiang, C.; Zhao, P.; Li, W.; Tang, Y.; Liu, G., In Silico Prediction of Chemical Neurotoxicity Using Machine Learning. Toxicol Res (Camb) 2020, 9 (3), 164–172.
