In silico Services

In Silico Modelling

Bayesian network

  • Our in silico modelling and in vitro testing workflows are anchored to key events of Adverse Outcome Pathways (AOPs)
  • We can apply a variety of algorithms and machine learning techniques to SaferSkin™ datasets supporting the building of reference and customised models
  • For skin sensitization we have reproduced the leading defined approaches developed and used at industry leaders such as P&G, BASF, Givaudan and Shiseido and including a well-documented and easy-to-use comparison of model results

AI / Machine Learning

  • We have leading expertise in developing and validating QSAR models
  • We apply our machine learning expertise to the development of models in SaferSkin™ applications including customised versions for customers
  • Our AI team has competency in extracting targeted knowledge from information collections (documents, abstracts etc.) and organising it as structured information e.g., available to applications from a customised EdelweissData™ instance

Data Management

  • Our EdelweissData™ approach to data management organises all data within our system using best data practices and standards
  • All metadata and data is harmonised and aims for completeness and integrity
  • Data processing workflows are organised as reproducible in silico protocols with instances stored within the system for future reference
  • All in silico and in vitro protocols are fully described and stored in the system
  • Secure customer data management solutions can be provided through premium customer accounts on a secure cloud


SaferWorldbyDesign integrates in silico and in vitro methods to develop standard and premium Integrated Approaches to Testing and Assessment (IATAs), including methods that support ingredient and formulation screening and testing, product design and the preparation of Regulatory Dossiers.


Edelweiss Connect GmbH is registered as a limited company with Handelsregisteramt of Kanton Basel-Stadt

Swiss ID (UID) number: CHE-114.414.615

Copyright | SaferWorldbyDesign 2022