Differentiated HepaRG™ cells

HepaRG® cells, catalog number HPR116 are cryopreserved after differentiation using a proprietary process developed by Biopredic International. A few days after thaw and culture, the cells will form a coculture of hepatocytes and of biliary epithelial-like cells.
Gripon P. et al. Proc. Natl. Acad. Sci. 99, 15655-15660, 2002.

All customers and recipients of cryopreserved differentiated HepaRG™ cells commit to accept the terms set in the Limited Use License Agreement below:

HepaRG® Cells are patented and their use is strictly limited; consider the Cells as a single-use, disposable product that must be destroyed upon the conclusion of an experiment. Propagating, reproducing, cloning, subcloning, or any other use of the cells following the conclusion of a study is prohibited. The use of the Cells to produce or manufacture commercial products for general sale or for use in the manufacture of products intended for general sale is prohibited, and their use is strictly limited to in-vitro studies. With the exception of Cells cultured and exposed to chemicals in the recipient facility and then sent to a collaborating laboratory for analytical purposes, transfer of the Cells to anyone not employed in the same organization or not in the same facility, whether for financial benefit or not, is prohibited. In such cases, the recipient bears the responsibility to ensure that the collaborating analytical laboratory disposes of the Cells immediately upon the conclusion of its analytical studies with the Cells. No resale of the product for any use is allowed. The recipient has no right to transfer, propagate, modify, derivatives, genetically engineer or otherwise create variations of the Cells. For sake of clarity, use of the Cells in contract studies is permitted provided that all restrictions herein on the transfer of the Cells are followed.
If you are unwilling to accept the terms of this LULA, do not order or use the Cells, and if you have received them, return them immediately for credit. Violators of this LULA will be prosecuted to the fullest extent of the law.

  • 1 mL vial with 10 x 10E+6 viable cells
  • 1 mL vial with 12 x 10E+6 viable cells
  • 1 mL vial with 8 x 10E+6 viable cells